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Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

Multiple system atrophy (MSA) is a horrible and unrelenting neurodegenerative disorder with an uncertain etiology and pathophysiology. MSA is a unique proteinopathy in which alpha-synuclein (α-syn) accumulates preferentially in oligodendroglia rather than neurons. Glial cytoplasmic inclusions (GCIs)...

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Detalles Bibliográficos
Autores principales:	Mandel, Ronald J., Marmion, David J., Kirik, Deniz, Chu, Yaping, Heindel, Clifford, McCown, Thomas, Gray, Steven J., Kordower, Jeffrey H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473003/ https://www.ncbi.nlm.nih.gov/pubmed/28619074 http://dx.doi.org/10.1186/s40478-017-0451-7

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