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Living with the Effects of Cutaneous Toxicities Induced by Treatment

The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Ta...

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Autor principal: Charalambous, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473093/
https://www.ncbi.nlm.nih.gov/pubmed/28695168
http://dx.doi.org/10.4103/2347-5625.207729
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author Charalambous, Andreas
author_facet Charalambous, Andreas
author_sort Charalambous, Andreas
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description The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Targeted therapies such as epidermal growth factor receptor, vascular endothelial growth factor receptor, kit, platelet-derived growth factor receptor, and BCR-ABL inhibitors as well as mammalian target of rapamycin inhibitors can induce cutaneous toxicities of varying severity. There are scarce studies on the actual impact of these toxicities on the patients' lives including the physical, social, and psychological aspects and overall quality of life. Patient's perspective in living with and beyond these toxicities remains largely uncharted but essential in optimizing care provided to those receiving treatment with targeted therapies.
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spelling pubmed-54730932017-07-11 Living with the Effects of Cutaneous Toxicities Induced by Treatment Charalambous, Andreas Asia Pac J Oncol Nurs Review Article The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Targeted therapies such as epidermal growth factor receptor, vascular endothelial growth factor receptor, kit, platelet-derived growth factor receptor, and BCR-ABL inhibitors as well as mammalian target of rapamycin inhibitors can induce cutaneous toxicities of varying severity. There are scarce studies on the actual impact of these toxicities on the patients' lives including the physical, social, and psychological aspects and overall quality of life. Patient's perspective in living with and beyond these toxicities remains largely uncharted but essential in optimizing care provided to those receiving treatment with targeted therapies. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5473093/ /pubmed/28695168 http://dx.doi.org/10.4103/2347-5625.207729 Text en Copyright: © 2017 Ann & Joshua Medical Publishing Co. Ltd http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Charalambous, Andreas
Living with the Effects of Cutaneous Toxicities Induced by Treatment
title Living with the Effects of Cutaneous Toxicities Induced by Treatment
title_full Living with the Effects of Cutaneous Toxicities Induced by Treatment
title_fullStr Living with the Effects of Cutaneous Toxicities Induced by Treatment
title_full_unstemmed Living with the Effects of Cutaneous Toxicities Induced by Treatment
title_short Living with the Effects of Cutaneous Toxicities Induced by Treatment
title_sort living with the effects of cutaneous toxicities induced by treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473093/
https://www.ncbi.nlm.nih.gov/pubmed/28695168
http://dx.doi.org/10.4103/2347-5625.207729
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