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Living with the Effects of Cutaneous Toxicities Induced by Treatment
The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Ta...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473093/ https://www.ncbi.nlm.nih.gov/pubmed/28695168 http://dx.doi.org/10.4103/2347-5625.207729 |
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author | Charalambous, Andreas |
author_facet | Charalambous, Andreas |
author_sort | Charalambous, Andreas |
collection | PubMed |
description | The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Targeted therapies such as epidermal growth factor receptor, vascular endothelial growth factor receptor, kit, platelet-derived growth factor receptor, and BCR-ABL inhibitors as well as mammalian target of rapamycin inhibitors can induce cutaneous toxicities of varying severity. There are scarce studies on the actual impact of these toxicities on the patients' lives including the physical, social, and psychological aspects and overall quality of life. Patient's perspective in living with and beyond these toxicities remains largely uncharted but essential in optimizing care provided to those receiving treatment with targeted therapies. |
format | Online Article Text |
id | pubmed-5473093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-54730932017-07-11 Living with the Effects of Cutaneous Toxicities Induced by Treatment Charalambous, Andreas Asia Pac J Oncol Nurs Review Article The introduction of targeted therapies in cancer treatment was accompanied with promising results including tumor control and patients survival benefits. However, these drugs just like their predecessors were associated with systemic side effects, including frequent and various cutaneous effects. Targeted therapies such as epidermal growth factor receptor, vascular endothelial growth factor receptor, kit, platelet-derived growth factor receptor, and BCR-ABL inhibitors as well as mammalian target of rapamycin inhibitors can induce cutaneous toxicities of varying severity. There are scarce studies on the actual impact of these toxicities on the patients' lives including the physical, social, and psychological aspects and overall quality of life. Patient's perspective in living with and beyond these toxicities remains largely uncharted but essential in optimizing care provided to those receiving treatment with targeted therapies. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5473093/ /pubmed/28695168 http://dx.doi.org/10.4103/2347-5625.207729 Text en Copyright: © 2017 Ann & Joshua Medical Publishing Co. Ltd http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Charalambous, Andreas Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title | Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title_full | Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title_fullStr | Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title_full_unstemmed | Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title_short | Living with the Effects of Cutaneous Toxicities Induced by Treatment |
title_sort | living with the effects of cutaneous toxicities induced by treatment |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473093/ https://www.ncbi.nlm.nih.gov/pubmed/28695168 http://dx.doi.org/10.4103/2347-5625.207729 |
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