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Experience-dependent epigenomic reorganization in the hippocampus

Using a hippocampus-dependent contextual threat learning and memory task, we report widespread, coordinated DNA methylation changes in CA1 hippocampus of Sprague-Dawley rats specific to threat learning at genes involved in synaptic transmission. Experience-dependent alternations in gene expression a...

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Detalles Bibliográficos
Autores principales:	Duke, Corey G., Kennedy, Andrew J., Gavin, Cristin F., Day, Jeremy J., Sweatt, J. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473107/ https://www.ncbi.nlm.nih.gov/pubmed/28620075 http://dx.doi.org/10.1101/lm.045112.117

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