Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor

Alteration of ryanodine receptor (RyR)-mediated calcium (Ca(2+)) signaling has been reported in Alzheimer disease (AD) models. However, the molecular mechanisms underlying altered RyR-mediated intracellular Ca(2+) release in AD remain to be fully elucidated. We report here that RyR2 undergoes post-t...

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Detalles Bibliográficos
Autores principales: Bussiere, Renaud, Lacampagne, Alain, Reiken, Steven, Liu, Xiaoping, Scheuerman, Valerie, Zalk, Ran, Martin, Cécile, Checler, Frederic, Marks, Andrew R., Chami, Mounia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473221/
https://www.ncbi.nlm.nih.gov/pubmed/28476886
http://dx.doi.org/10.1074/jbc.M116.743070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473221/
https://www.ncbi.nlm.nih.gov/pubmed/28476886
http://dx.doi.org/10.1074/jbc.M116.743070

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