Cargando…

Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo

Background: Micronemal proteins of the thrombospondin-related anonymous protein (TRAP) family are believed to play essential roles during gliding motility and host cell invasion by apicomplexan parasites, and currently represent major vaccine candidates against Plasmodium falciparum, the causative a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gras, Simon, Jackson, Allison, Woods, Stuart, Pall, Gurman, Whitelaw, Jamie, Leung, Jacqueline M., Ward, Gary E., Roberts, Craig W., Meissner, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473411/ https://www.ncbi.nlm.nih.gov/pubmed/28630943 http://dx.doi.org/10.12688/wellcomeopenres.11594.2

Ejemplares similares

Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum
por: Wang, Xianmei, et al.
Publicado: (2021)

Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion
por: Whitelaw, Jamie A., et al.
Publicado: (2017)

Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8)
por: Zhao, Ningning, et al.
Publicado: (2021)

Identification of a TNF-α inducer MIC3 originating from the microneme of non-cystogenic, virulent Toxoplasma gondii
por: Qiu, Jingfan, et al.
Publicado: (2016)

Effects of Estradiol and Progesterone-Induced Intracellular Calcium Fluxes on Toxoplasma gondii Gliding, Microneme Secretion, and Egress
por: Zhang, Xiao, et al.
Publicado: (2018)

Synergistic role of micronemal proteins in Toxoplasma gondii virulence
por: Cérède, Odile, et al.
Publicado: (2005)

The microneme adhesive repeat domain of MIC3 protein determined the site specificity of Eimeria acervulina, Eimeria maxima, and Eimeria mitis
por: Zhang, Yang, et al.
Publicado: (2023)

Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion
por: Bargieri, Daniel Y., et al.
Publicado: (2013)

A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles
por: Periz, Javier, et al.
Publicado: (2019)

Malaria parasite egress at a glance
por: Tan, Michele S. Y, et al.
Publicado: (2021)

Identification of host proteins interacting with the integrin-like A domain of Toxoplasma gondii micronemal protein MIC2 by yeast-two-hybrid screening
por: Wang, Yifan, et al.
Publicado: (2014)

An Ancient Protein Phosphatase, SHLP1, Is Critical to Microneme Development in Plasmodium Ookinetes and Parasite Transmission
por: Patzewitz, Eva-Maria, et al.
Publicado: (2013)

Motility precedes egress of malaria parasites from oocysts
por: Klug, Dennis, et al.
Publicado: (2017)

Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division
por: Venugopal, Kannan, et al.
Publicado: (2017)

Glycosylphosphatidylinositol-anchored micronemal antigen (GAMA) interacts with the band 3 receptor to promote erythrocyte invasion by malaria parasites
por: Lu, Jiachen, et al.
Publicado: (2022)

Toxoplasma gondii microneme protein MIC3 induces macrophage TNF-α production and Ly6C expression via TLR11/MyD88 pathway
por: Qiu, Jingfan, et al.
Publicado: (2023)

Identification and Molecular Characterization of Microneme 5 of Eimeria acervulina
por: Zhang, ZhenChao, et al.
Publicado: (2014)

Research advances in microneme protein 3 of Toxoplasma gondii
por: Wang, Yanhua, et al.
Publicado: (2015)

An Overexpression Screen of Toxoplasma gondii Rab-GTPases Reveals Distinct Transport Routes to the Micronemes
por: Kremer, Katrin, et al.
Publicado: (2013)

The Toxoplasma Acto-MyoA Motor Complex Is Important but Not Essential for Gliding Motility and Host Cell Invasion
por: Egarter, Saskia, et al.
Publicado: (2014)

Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella
por: Marugan-Hernandez, Virginia, et al.
Publicado: (2017)

Toxoplasma MIC2 Is a Major Determinant of Invasion and Virulence
por: Huynh, My-Hang, et al.
Publicado: (2006)

Reduced Parasite Motility and Micronemal Protein Secretion by a p38 MAPK Inhibitor Leads to a Severe Impairment of Cell Invasion by the Apicomplexan Parasite Eimeria tenella
por: Bussière, Françoise I., et al.
Publicado: (2015)

Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the Toxoplasma Micronemes
por: Saha, Sudeshna, et al.
Publicado: (2017)

Recent progress in microneme-based vaccines development against Toxoplasma gondii
por: Foroutan, Masoud, et al.
Publicado: (2018)

Immunogenicity of glycosylphosphatidylinositol-anchored micronemal antigen in natural Plasmodium vivax exposure
por: Changrob, Siriruk, et al.
Publicado: (2017)

A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma
por: Valleau, Dylan, et al.
Publicado: (2023)

Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
Publicado: (1976)

Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress
por: Glushakova, Svetlana, et al.
Publicado: (2017)

LISP1 is important for the egress of Plasmodium berghei parasites from liver cells
por: Ishino, Tomoko, et al.
Publicado: (2009)

The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress
por: Perrin, Abigail J., et al.
Publicado: (2018)

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
por: Nasamu, Armiyaw S., et al.
Publicado: (2017)

A malaria parasite phospholipase facilitates efficient asexual blood stage egress
por: Ramaprasad, Abhinay, et al.
Publicado: (2023)

Discovery of New Microneme Proteins in Cryptosporidium parvum and Implication of the Roles of a Rhomboid Membrane Protein (CpROM1) in Host–Parasite Interaction
por: Gao, Xin, et al.
Publicado: (2021)

Apicomplexan F‐actin is required for efficient nuclear entry during host cell invasion
por: Del Rosario, Mario, et al.
Publicado: (2019)

Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice
por: Pinzan, Camila Figueiredo, et al.
Publicado: (2015)

Molecular characterization and protective efficacy of the microneme 2 protein from Eimeria tenella
por: Yan, Ming, et al.
Publicado: (2018)

Expression Analysis and Serodiagnostic Potential of Microneme Proteins 1 and 3 in Eimeria stiedai
por: Wei, Wenrui, et al.
Publicado: (2020)

Ferlins and TgDOC2 in Toxoplasma Microneme, Rhoptry and Dense Granule Secretion
por: Tagoe, Daniel N. A., et al.
Publicado: (2021)

Genetic Diversity of Microneme Protein 2 and Surface Antigen 1 of Eimeria tenella
por: Võ, Tuấn Cường, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lnv416oq8febnn6gekaqhge2e6