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Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men

We assessed spontaneous clearance in 27 human immunodeficiency virus–infected men who have sex with men (MSM) who seroconverted for hepatitis C virus (HCV). In contrast with a recent estimate of 45.8%, we found a spontaneous clearance rate of 11.1% (95% confidence interval = 2.4–29.2). This finding...

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Autores principales: Newsum, Astrid M., Schinkel, Janke, van de Laar, Thijs J. W., van der Meer, Jan T. M., Prins, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473437/
https://www.ncbi.nlm.nih.gov/pubmed/28638847
http://dx.doi.org/10.1093/ofid/ofx090
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author Newsum, Astrid M.
Schinkel, Janke
van de Laar, Thijs J. W.
van der Meer, Jan T. M.
Prins, Maria
author_facet Newsum, Astrid M.
Schinkel, Janke
van de Laar, Thijs J. W.
van der Meer, Jan T. M.
Prins, Maria
author_sort Newsum, Astrid M.
collection PubMed
description We assessed spontaneous clearance in 27 human immunodeficiency virus–infected men who have sex with men (MSM) who seroconverted for hepatitis C virus (HCV). In contrast with a recent estimate of 45.8%, we found a spontaneous clearance rate of 11.1% (95% confidence interval = 2.4–29.2). This finding suggests that treatment deferral to await spontaneous clearance might not be justified for MSM with sexually acquired HCV.
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spelling pubmed-54734372017-06-21 Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men Newsum, Astrid M. Schinkel, Janke van de Laar, Thijs J. W. van der Meer, Jan T. M. Prins, Maria Open Forum Infect Dis Brief Report We assessed spontaneous clearance in 27 human immunodeficiency virus–infected men who have sex with men (MSM) who seroconverted for hepatitis C virus (HCV). In contrast with a recent estimate of 45.8%, we found a spontaneous clearance rate of 11.1% (95% confidence interval = 2.4–29.2). This finding suggests that treatment deferral to await spontaneous clearance might not be justified for MSM with sexually acquired HCV. Oxford University Press 2017-06-16 /pmc/articles/PMC5473437/ /pubmed/28638847 http://dx.doi.org/10.1093/ofid/ofx090 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Newsum, Astrid M.
Schinkel, Janke
van de Laar, Thijs J. W.
van der Meer, Jan T. M.
Prins, Maria
Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title_full Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title_fullStr Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title_full_unstemmed Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title_short Spontaneous Clearance of Hepatitis C Virus Infection Among Human Immunodeficiency Virus–Infected Men Who Have Sex With Men
title_sort spontaneous clearance of hepatitis c virus infection among human immunodeficiency virus–infected men who have sex with men
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473437/
https://www.ncbi.nlm.nih.gov/pubmed/28638847
http://dx.doi.org/10.1093/ofid/ofx090
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