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Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma
Brentuximab vedotin is an antibody-conjugated chemotherapy targeting CD30 indicated in treatment of several lymphomas. We report the first 3 cases of cytomegalovirus severe infections with retinitis following this treatment. Evolution was favorable, but relapse occurred after treatment rechallenge....
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473439/ https://www.ncbi.nlm.nih.gov/pubmed/28638848 http://dx.doi.org/10.1093/ofid/ofx091 |
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author | Tudesq, Jean-Jacques Vincent, Laure Lebrun, Julie Hicheri, Yosr Gabellier, Ludovic Busetto, Timothé Merle, Corinne Fegueux, Nathalie Ceballos, Patrice Quittet, Philippe Navarro, Robert Hillaire-Buys, Dominique Cartron, Guillaume |
author_facet | Tudesq, Jean-Jacques Vincent, Laure Lebrun, Julie Hicheri, Yosr Gabellier, Ludovic Busetto, Timothé Merle, Corinne Fegueux, Nathalie Ceballos, Patrice Quittet, Philippe Navarro, Robert Hillaire-Buys, Dominique Cartron, Guillaume |
author_sort | Tudesq, Jean-Jacques |
collection | PubMed |
description | Brentuximab vedotin is an antibody-conjugated chemotherapy targeting CD30 indicated in treatment of several lymphomas. We report the first 3 cases of cytomegalovirus severe infections with retinitis following this treatment. Evolution was favorable, but relapse occurred after treatment rechallenge. We suggest vigilance about cytomegalovirus in patients treated with brentuximab vedotin. |
format | Online Article Text |
id | pubmed-5473439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-54734392017-06-21 Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma Tudesq, Jean-Jacques Vincent, Laure Lebrun, Julie Hicheri, Yosr Gabellier, Ludovic Busetto, Timothé Merle, Corinne Fegueux, Nathalie Ceballos, Patrice Quittet, Philippe Navarro, Robert Hillaire-Buys, Dominique Cartron, Guillaume Open Forum Infect Dis Brief Report Brentuximab vedotin is an antibody-conjugated chemotherapy targeting CD30 indicated in treatment of several lymphomas. We report the first 3 cases of cytomegalovirus severe infections with retinitis following this treatment. Evolution was favorable, but relapse occurred after treatment rechallenge. We suggest vigilance about cytomegalovirus in patients treated with brentuximab vedotin. Oxford University Press 2017-04-05 /pmc/articles/PMC5473439/ /pubmed/28638848 http://dx.doi.org/10.1093/ofid/ofx091 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Brief Report Tudesq, Jean-Jacques Vincent, Laure Lebrun, Julie Hicheri, Yosr Gabellier, Ludovic Busetto, Timothé Merle, Corinne Fegueux, Nathalie Ceballos, Patrice Quittet, Philippe Navarro, Robert Hillaire-Buys, Dominique Cartron, Guillaume Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title | Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title_full | Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title_fullStr | Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title_full_unstemmed | Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title_short | Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30(+) Lymphoma |
title_sort | cytomegalovirus infection with retinitis after brentuximab vedotin treatment for cd30(+) lymphoma |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473439/ https://www.ncbi.nlm.nih.gov/pubmed/28638848 http://dx.doi.org/10.1093/ofid/ofx091 |
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