Principles of early human development and germ cell program from conserved model systems

Human primordial germ cells (hPGCs), the precursors of sperm and eggs, originate during week 2-3 of early postimplantation development1. Using in vitro models of hPGC induction2–4, recent studies suggest striking mechanistic differences in specification of human and mouse PGCs5. This may partly be d...

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Detalles Bibliográficos
Autores principales: Kobayashi, Toshihiro, Zhang, Haixin, Tang, Walfred W.C., Irie, Naoko, Withey, Sarah, Klisch, Doris, Sybirna, Anastasiya, Dietmann, Sabine, Contreras, David A., Webb, Robert, Allegrucci, Cinzia, Alberio, Ramiro, Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473469/
https://www.ncbi.nlm.nih.gov/pubmed/28607482
http://dx.doi.org/10.1038/nature22812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473469/
https://www.ncbi.nlm.nih.gov/pubmed/28607482
http://dx.doi.org/10.1038/nature22812

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