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A Bayesian adaptive design for clinical trials in rare diseases
Development of treatments for rare diseases is challenging due to the limited number of patients available for participation. Learning about treatment effectiveness with a view to treat patients in the larger outside population, as in the traditional fixed randomised design, may not be a plausible g...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473477/ https://www.ncbi.nlm.nih.gov/pubmed/28630525 http://dx.doi.org/10.1016/j.csda.2016.09.006 |