Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

Innovative therapies for solid tumors are urgently needed. Recently, therapies that harness the host immune system to fight cancer cells have successfully treated a subset of patients with solid tumors. These responses have been strong and durable but observed in subsets of patients. Work from our g...

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Detalles Bibliográficos
Autores principales: Siebenkäs, Cornelia, Chiappinelli, Katherine B., Guzzetta, Angela A., Sharma, Anup, Jeschke, Jana, Vatapalli, Rajita, Baylin, Stephen B., Ahuja, Nita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473589/
https://www.ncbi.nlm.nih.gov/pubmed/28622390
http://dx.doi.org/10.1371/journal.pone.0179501

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