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Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28

Cdk1 (Cdc28 in yeast) is a cyclin-dependent kinase (CDK) essential for cell cycle progression and cell division in normal cells. However, CDK activity also underpins proliferation of tumor cells, making it a relevant study subject. While numerous targets and processes regulated by Cdc28 have been id...

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Detalles Bibliográficos
Autores principales:	Zimmermann, Christine, Garcia, Ignacio, Omerzu, Manja, Chymkowitch, Pierre, Zhang, Beibei, Enserink, Jorrit M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473755/ https://www.ncbi.nlm.nih.gov/pubmed/28428242 http://dx.doi.org/10.1534/g3.117.042317

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