Structural and Biochemical Characterization of Poly-ADP-ribose Polymerase from Trypanosoma brucei

Trypanosoma brucei is a unicellular parasite responsible for African trypanosomiasis or sleeping sickness. It contains a single PARP enzyme opposed to many higher eukaryotes, which have numerous PARPs. PARPs are responsible for a post-translational modification, ADP-ribosylation, regulating a multit...

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Detalles Bibliográficos
Autores principales: Haikarainen, Teemu, Schlesinger, Mariana, Obaji, Ezeogo, Fernández Villamil, Silvia H., Lehtiö, Lari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473844/
https://www.ncbi.nlm.nih.gov/pubmed/28623292
http://dx.doi.org/10.1038/s41598-017-03751-4

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