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Inhibition of Calpains Protects Mn-Induced Neurotransmitter release disorders in Synaptosomes from Mice: Involvement of SNARE Complex and Synaptic Vesicle Fusion

Overexposure to manganese (Mn) could disrupt neurotransmitter release via influencing the formation of SNARE complex, but the underlying mechanisms are still unclear. A previous study demonstrated that SNAP-25 is one of substrate of calpains. The current study investigated whether calpains were invo...

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Detalles Bibliográficos
Autores principales:	Wang, Can, Xu, Bin, Ma, Zhuo, Liu, Chang, Deng, Yu, Liu, Wei, Xu, Zhao-Fa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473846/ https://www.ncbi.nlm.nih.gov/pubmed/28623313 http://dx.doi.org/10.1038/s41598-017-04017-9

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