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Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy

The human chaperonin TRiC consists of eight non-identical subunits, and its protein-folding activity is critical for cellular health. Misfolded proteins are associated with many human diseases, such as amyloid diseases, cancer, and neuropathies, making TRiC a potential therapeutic target. A detailed...

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Detalles Bibliográficos
Autores principales:	Pereira, Jose H., McAndrew, Ryan P., Sergeeva, Oksana A., Ralston, Corie Y., King, Jonathan A., Adams, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473854/ https://www.ncbi.nlm.nih.gov/pubmed/28623285 http://dx.doi.org/10.1038/s41598-017-03825-3

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