Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts with the...

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Detalles Bibliográficos
Autores principales: Desravines, Danielle C., Serna Martin, Itziar, Schneider, Robert, Mas, Philippe J., Aleksandrova, Nataliia, Jensen, Malene Ringkjøbing, Blackledge, Martin, Hart, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473869/
https://www.ncbi.nlm.nih.gov/pubmed/28623264
http://dx.doi.org/10.1038/s41598-017-03718-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473869/
https://www.ncbi.nlm.nih.gov/pubmed/28623264
http://dx.doi.org/10.1038/s41598-017-03718-5

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