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A new paradigm for antiangiogenic therapy through controlled release of bevacizumab from PLGA nanoparticles
Monoclonal antibodies have deserved a remarkable interest for more than 40 years as a vital tool for the treatment of various diseases. Still, there is a raising interest to develop advanced monoclonal antibody delivery systems able to tailor pharmacokinetics. Bevacizumab is a humanized immunoglobul...
Autores principales: | Sousa, Flávia, Cruz, Andrea, Fonte, Pedro, Pinto, Inês Mendes, Neves-Petersen, Maria Teresa, Sarmento, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473878/ https://www.ncbi.nlm.nih.gov/pubmed/28623267 http://dx.doi.org/10.1038/s41598-017-03959-4 |
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