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Constraint-based modeling identifies new putative targets to fight colistin-resistant A. baumannii infections

Acinetobacter baumannii is a clinical threat to human health, causing major infection outbreaks worldwide. As new drugs against Gram-negative bacteria do not seem to be forthcoming, and due to the microbial capability of acquiring multi-resistance, there is an urgent need for novel therapeutic targe...

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Detalles Bibliográficos
Autores principales: Presta, Luana, Bosi, Emanuele, Mansouri, Leila, Dijkshoorn, Lenie, Fani, Renato, Fondi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473915/
https://www.ncbi.nlm.nih.gov/pubmed/28623298
http://dx.doi.org/10.1038/s41598-017-03416-2