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Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells

Articular chondrocytes are slowly dividing cells that tend to lose their cell type-specific phenotype and ability to produce structurally and functionally correct cartilage tissue when cultured. Thus, culture conditions, which enhance the maintenance of chondrocyte phenotype would be very useful for...

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Detalles Bibliográficos
Autores principales:	Piltti, Juha, Bygdell, Joakim, Fernández-Echevarría, Cecilia, Marcellino, Daniel, Lammi, Mikko J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473921/ https://www.ncbi.nlm.nih.gov/pubmed/28623370 http://dx.doi.org/10.1038/s41598-017-03958-5

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