One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond

BACKGROUND: Hyperhomocysteinemia is a risk factor for cognitive decline and dementia, including Alzheimer disease (AD). Homocysteine (Hcy) is a sulfur-containing amino acid and metabolite of the methionine pathway. The interrelated methionine, purine, and thymidylate cycles constitute the one-carbon...

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Detalles Bibliográficos
Autores principales: Dayon, Loïc, Guiraud, Seu Ping, Corthésy, John, Da Silva, Laeticia, Migliavacca, Eugenia, Tautvydaitė, Domilė, Oikonomidi, Aikaterini, Moullet, Barbara, Henry, Hugues, Métairon, Sylviane, Marquis, Julien, Descombes, Patrick, Collino, Sebastiano, Martin, François-Pierre J., Montoliu, Ivan, Kussmann, Martin, Wojcik, Jérôme, Bowman, Gene L., Popp, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473969/
https://www.ncbi.nlm.nih.gov/pubmed/28623948
http://dx.doi.org/10.1186/s13195-017-0270-x

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