DNA sequence homology induces cytosine-to-thymine mutation by a heterochromatin-related pathway in Neurospora

Eukaryotic genomes contain substantial amounts of repetitive DNA organized in the form of constitutive heterochromatin and associated with repressive epigenetic modifications, such as H3K9me3 and C5-cytosine methylation (5mC). In the fungus Neurospora crassa, H3K9me3 and 5mC are catalyzed, respectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Gladyshev, Eugene, Kleckner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474309/
https://www.ncbi.nlm.nih.gov/pubmed/28459455
http://dx.doi.org/10.1038/ng.3857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474309/
https://www.ncbi.nlm.nih.gov/pubmed/28459455
http://dx.doi.org/10.1038/ng.3857

Ejemplares similares