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DNA sequence homology induces cytosine-to-thymine mutation by a heterochromatin-related pathway in Neurospora
Eukaryotic genomes contain substantial amounts of repetitive DNA organized in the form of constitutive heterochromatin and associated with repressive epigenetic modifications, such as H3K9me3 and C5-cytosine methylation (5mC). In the fungus Neurospora crassa, H3K9me3 and 5mC are catalyzed, respectiv...
Autores principales: | Gladyshev, Eugene, Kleckner, Nancy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474309/ https://www.ncbi.nlm.nih.gov/pubmed/28459455 http://dx.doi.org/10.1038/ng.3857 |
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