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Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis
BACKGROUND: Recently alternative therapies such as the use of diode laser therapy have been introduced for recurrent herpes labial infection. The aim of this study was to evaluate the effectiveness of diode laser for treatment of recurrent herpes labialis. MATERIAL AND METHODS: This was single-blind...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474325/ https://www.ncbi.nlm.nih.gov/pubmed/28638546 http://dx.doi.org/10.4317/jced.53679 |
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author | Honarmand, Marieh Farhadmollashahi, Leila Vosoughirahbar, Ehsan |
author_facet | Honarmand, Marieh Farhadmollashahi, Leila Vosoughirahbar, Ehsan |
author_sort | Honarmand, Marieh |
collection | PubMed |
description | BACKGROUND: Recently alternative therapies such as the use of diode laser therapy have been introduced for recurrent herpes labial infection. The aim of this study was to evaluate the effectiveness of diode laser for treatment of recurrent herpes labialis. MATERIAL AND METHODS: This was single-blind randomized clinical trial to evaluate the efficacy of diode laser for the treatment of recurrent herpes labial. In total, 60 patients whit recurrent herpes simplex labialis were selected and randomly divided in to three groups. 20 patients received treatment whit diode laser (at a wavelength of 870 nm, energy density 4.5 j/cm2), 20 patients were treated with acyclovir cream 5%, 20 patients received treatment with laser-off (placebo). The end point was lesions crusting. Data analyzed by Tukey HSD Test and One-way ANOVA (at a significance level of 0.05) in SPSS-20 software. RESULTS: The mean length of recovery time (day) in the laser, off laser, and acyclovir groups was 2.20±0.41, 4.30±1.03, and 3.4±1.142, respectively. There is a significant difference between three groups in this regard (P<0.0001). The mean duration of pain (day) was 1.35±0.74, 2.65±1.27, and 2.30±0.92 for laser, off laser, and acyclovir groups, respectively (P<0.0001). CONCLUSIONS: Treatment with diode laser reduced the length of recovery time and pain severity faster than treatment with acyclovir cream. Key words:Recurrent herpes labial, Acyclovir, Low level laser therapy. |
format | Online Article Text |
id | pubmed-5474325 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-54743252017-06-21 Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis Honarmand, Marieh Farhadmollashahi, Leila Vosoughirahbar, Ehsan J Clin Exp Dent Research BACKGROUND: Recently alternative therapies such as the use of diode laser therapy have been introduced for recurrent herpes labial infection. The aim of this study was to evaluate the effectiveness of diode laser for treatment of recurrent herpes labialis. MATERIAL AND METHODS: This was single-blind randomized clinical trial to evaluate the efficacy of diode laser for the treatment of recurrent herpes labial. In total, 60 patients whit recurrent herpes simplex labialis were selected and randomly divided in to three groups. 20 patients received treatment whit diode laser (at a wavelength of 870 nm, energy density 4.5 j/cm2), 20 patients were treated with acyclovir cream 5%, 20 patients received treatment with laser-off (placebo). The end point was lesions crusting. Data analyzed by Tukey HSD Test and One-way ANOVA (at a significance level of 0.05) in SPSS-20 software. RESULTS: The mean length of recovery time (day) in the laser, off laser, and acyclovir groups was 2.20±0.41, 4.30±1.03, and 3.4±1.142, respectively. There is a significant difference between three groups in this regard (P<0.0001). The mean duration of pain (day) was 1.35±0.74, 2.65±1.27, and 2.30±0.92 for laser, off laser, and acyclovir groups, respectively (P<0.0001). CONCLUSIONS: Treatment with diode laser reduced the length of recovery time and pain severity faster than treatment with acyclovir cream. Key words:Recurrent herpes labial, Acyclovir, Low level laser therapy. Medicina Oral S.L. 2017-06-01 /pmc/articles/PMC5474325/ /pubmed/28638546 http://dx.doi.org/10.4317/jced.53679 Text en Copyright: © 2017 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Honarmand, Marieh Farhadmollashahi, Leila Vosoughirahbar, Ehsan Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis |
title | Comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
title_full | Comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
title_fullStr | Comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
title_full_unstemmed | Comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
title_short | Comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
title_sort | comparing the effect of diode laser against acyclovir
cream for the treatment of herpes labialis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474325/ https://www.ncbi.nlm.nih.gov/pubmed/28638546 http://dx.doi.org/10.4317/jced.53679 |
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