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Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium
Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment. Here we demonstrate that glutamine catabolism (glu...
Autores principales: | Zhang, Wenlin, Li, Hongde, Ogando, Diego G., Li, Shimin, Feng, Matthew, Price, Francis W., Tennessen, Jason M., Bonanno, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474426/ https://www.ncbi.nlm.nih.gov/pubmed/28117276 http://dx.doi.org/10.1016/j.ebiom.2017.01.004 |
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