p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo

p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs in the presence of oxidative stress mediated by doxorubicin in vitro and type-1 diabetes in vivo. CPCs were o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kannappan, Ramaswamy, Matsuda, Alex, Ferreira-Martins, João, Zhang, Eric, Palano, Giorgia, Czarna, Anna, Cabral-Da-Silva, Mauricio Castro, Bastos-Carvalho, Adriana, Sanada, Fumihiro, Ide, Noriko, Rota, Marcello, Blasco, Maria A., Serrano, Manuel, Anversa, Piero, Leri, Annarosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474510/
https://www.ncbi.nlm.nih.gov/pubmed/28163043
http://dx.doi.org/10.1016/j.ebiom.2017.01.028

Ejemplares similares

Ejemplares similares