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The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis
The introduction of interferon beta therapies more than 20 years ago marked a milestone in the treatment of relapsing‐remitting multiple sclerosis (RRMS) with a significant impact on the approach to modern multiple sclerosis (MS) care. Key learnings and perspectives from the early days of disease mo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474703/ https://www.ncbi.nlm.nih.gov/pubmed/28638705 http://dx.doi.org/10.1002/brb3.696 |
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author | Madsen, Claus |
author_facet | Madsen, Claus |
author_sort | Madsen, Claus |
collection | PubMed |
description | The introduction of interferon beta therapies more than 20 years ago marked a milestone in the treatment of relapsing‐remitting multiple sclerosis (RRMS) with a significant impact on the approach to modern multiple sclerosis (MS) care. Key learnings and perspectives from the early days of disease modifying therapies in MS have improved the knowledge base of MS, need for treatment, and patient care. The continuous development of interferons over the past two decades outlines a journey with increased understanding of the pharmacodynamics and pharmacokinetic mechanisms of interferons, leading to innovative formulations with an improved benefit/risk profile. |
format | Online Article Text |
id | pubmed-5474703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-54747032017-06-21 The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis Madsen, Claus Brain Behav Review The introduction of interferon beta therapies more than 20 years ago marked a milestone in the treatment of relapsing‐remitting multiple sclerosis (RRMS) with a significant impact on the approach to modern multiple sclerosis (MS) care. Key learnings and perspectives from the early days of disease modifying therapies in MS have improved the knowledge base of MS, need for treatment, and patient care. The continuous development of interferons over the past two decades outlines a journey with increased understanding of the pharmacodynamics and pharmacokinetic mechanisms of interferons, leading to innovative formulations with an improved benefit/risk profile. John Wiley and Sons Inc. 2017-05-08 /pmc/articles/PMC5474703/ /pubmed/28638705 http://dx.doi.org/10.1002/brb3.696 Text en © 2017 The Author. Brain and Behavior published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Madsen, Claus The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title | The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title_full | The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title_fullStr | The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title_full_unstemmed | The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title_short | The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
title_sort | innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474703/ https://www.ncbi.nlm.nih.gov/pubmed/28638705 http://dx.doi.org/10.1002/brb3.696 |
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