Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report

BACKGROUND: We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. CASE PRESENTATION: A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood ana...

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Autores principales: Sindhu, Hemant, Chen, Ruqin, Chen, Hui, Wong, Jonathan, Chaudhry, Rashid, Xu, Yin, Wang, Jen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474878/
https://www.ncbi.nlm.nih.gov/pubmed/28625163
http://dx.doi.org/10.1186/s13256-017-1312-5
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author Sindhu, Hemant
Chen, Ruqin
Chen, Hui
Wong, Jonathan
Chaudhry, Rashid
Xu, Yin
Wang, Jen C.
author_facet Sindhu, Hemant
Chen, Ruqin
Chen, Hui
Wong, Jonathan
Chaudhry, Rashid
Xu, Yin
Wang, Jen C.
author_sort Sindhu, Hemant
collection PubMed
description BACKGROUND: We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. CASE PRESENTATION: A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was negative for lymphoma. Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system. CONCLUSIONS: We believe this is a case of not otherwise specified gamma-delta T-cell lymphoma. Accumulation of these rare not otherwise specified cases will be important for future classification which further defines the biology of this disease.
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spelling pubmed-54748782017-06-22 Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report Sindhu, Hemant Chen, Ruqin Chen, Hui Wong, Jonathan Chaudhry, Rashid Xu, Yin Wang, Jen C. J Med Case Rep Case Report BACKGROUND: We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. CASE PRESENTATION: A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was negative for lymphoma. Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system. CONCLUSIONS: We believe this is a case of not otherwise specified gamma-delta T-cell lymphoma. Accumulation of these rare not otherwise specified cases will be important for future classification which further defines the biology of this disease. BioMed Central 2017-06-19 /pmc/articles/PMC5474878/ /pubmed/28625163 http://dx.doi.org/10.1186/s13256-017-1312-5 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sindhu, Hemant
Chen, Ruqin
Chen, Hui
Wong, Jonathan
Chaudhry, Rashid
Xu, Yin
Wang, Jen C.
Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title_full Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title_fullStr Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title_full_unstemmed Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title_short Gamma-delta (γδ) T-cell lymphoma – another case unclassifiable by World Health Organization classification: a case report
title_sort gamma-delta (γδ) t-cell lymphoma – another case unclassifiable by world health organization classification: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474878/
https://www.ncbi.nlm.nih.gov/pubmed/28625163
http://dx.doi.org/10.1186/s13256-017-1312-5
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