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Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses

Recently, the World Health Organization confirmed 120 new human cases of avian H7N9 influenza in China resulting in 37 deaths, highlighting the concern for a potential pandemic and the need for an effective, safe, and high-speed vaccine production platform. Production speed and scale of mRNA-based v...

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Detalles Bibliográficos
Autores principales: Bahl, Kapil, Senn, Joe J., Yuzhakov, Olga, Bulychev, Alex, Brito, Luis A., Hassett, Kimberly J., Laska, Michael E., Smith, Mike, Almarsson, Örn, Thompson, James, Ribeiro, Amilcar (Mick), Watson, Mike, Zaks, Tal, Ciaramella, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475249/
https://www.ncbi.nlm.nih.gov/pubmed/28457665
http://dx.doi.org/10.1016/j.ymthe.2017.03.035