Vitamin A mediates conversion of monocyte-derived macrophages into tissue resident macrophages during alternative activation

Whether activated inflammatory macrophages can adopt features of tissue resident macrophages and what mechanisms mediate this phenotypic conversion remain unclear. Here we show that vitamin A was required for phenotypic conversion of interleukin 4 (IL-4)-activated monocyte-derived F4/80(int)CD206(+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Gundra, Uma Mahesh, Girgis, Natasha M, Gonzalez, Michael A, Tang, Mei San, Van Der Zande, Hendrik J P, Lin, Jian-Da, Ouimet, Mireille, Ma, Lily J, Poles, Jordan A, Vozhilla, Nikollaq, Fisher, Edward A, Moore, Kathryn J, Loke, P’ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475284/
https://www.ncbi.nlm.nih.gov/pubmed/28436955
http://dx.doi.org/10.1038/ni.3734

Ejemplares similares

Ejemplares similares