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Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China

BACKGROUND: Dysglycemia (pre-diabetes or diabetes) in young adults has increased rapidly. However, the risk scores for detecting dysglycemia in oil field staff and workers in China are limited. This study developed a risk score for the early identification of dysglycemia based on epidemiological and...

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Autores principales: Tian, Xiubiao, Liu, Yan, Han, Ying, Shi, Jieli, Zhu, Tiehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475373/
https://www.ncbi.nlm.nih.gov/pubmed/28601890
http://dx.doi.org/10.12659/MSM.904449
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author Tian, Xiubiao
Liu, Yan
Han, Ying
Shi, Jieli
Zhu, Tiehong
author_facet Tian, Xiubiao
Liu, Yan
Han, Ying
Shi, Jieli
Zhu, Tiehong
author_sort Tian, Xiubiao
collection PubMed
description BACKGROUND: Dysglycemia (pre-diabetes or diabetes) in young adults has increased rapidly. However, the risk scores for detecting dysglycemia in oil field staff and workers in China are limited. This study developed a risk score for the early identification of dysglycemia based on epidemiological and health examination data in an oil field working-age population with increased risk of diabetes. MATERIAL/METHODS: Multivariable logistic regression was used to develop the risk score model in a population-based, cross-sectional study. All subjects completed the questionnaires and underwent physical examination and oral glucose tolerance tests. The performance of the risk score models was evaluated using the area under the receiver operating characteristic curve (AUC). RESULTS: The study population consisted of 1995 participants, 20–64 years old (49.4% males), with undiagnosed diabetes or pre-diabetes who underwent periodic health examinations from March 2014 to June 2015 in Dagang oil field, Tianjin, China. Age, sex, body mass index, history of high blood glucose, smoking, triglyceride, and fasting plasma glucose (FPG) constituted the Dagang dysglycemia risk score (Dagang DRS) model. The performance of Dagang DRS was superior to m-FINDRISC (AUC: 0.791; 95% confidence interval (CI), 0.773–0.809 vs. 0.633; 95% CI, 0.611–0.654). At the cut-off value of 5.6 mmol/L, the Dagang DRS (AUC: 0.616; 95% CI, 0.592–0.641) was better than the FPG value alone (AUC: 0.571; 95% CI, 0.546–0.596) in participants with FPG <6.1 mmol/L (n=1545, P=0.028). CONCLUSIONS: Dagang DRS is a valuable tool for detecting dysglycemia, especially when FPG <6.1 mmol/L, in oil field workers in China.
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spelling pubmed-54753732017-06-28 Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China Tian, Xiubiao Liu, Yan Han, Ying Shi, Jieli Zhu, Tiehong Med Sci Monit Clinical Research BACKGROUND: Dysglycemia (pre-diabetes or diabetes) in young adults has increased rapidly. However, the risk scores for detecting dysglycemia in oil field staff and workers in China are limited. This study developed a risk score for the early identification of dysglycemia based on epidemiological and health examination data in an oil field working-age population with increased risk of diabetes. MATERIAL/METHODS: Multivariable logistic regression was used to develop the risk score model in a population-based, cross-sectional study. All subjects completed the questionnaires and underwent physical examination and oral glucose tolerance tests. The performance of the risk score models was evaluated using the area under the receiver operating characteristic curve (AUC). RESULTS: The study population consisted of 1995 participants, 20–64 years old (49.4% males), with undiagnosed diabetes or pre-diabetes who underwent periodic health examinations from March 2014 to June 2015 in Dagang oil field, Tianjin, China. Age, sex, body mass index, history of high blood glucose, smoking, triglyceride, and fasting plasma glucose (FPG) constituted the Dagang dysglycemia risk score (Dagang DRS) model. The performance of Dagang DRS was superior to m-FINDRISC (AUC: 0.791; 95% confidence interval (CI), 0.773–0.809 vs. 0.633; 95% CI, 0.611–0.654). At the cut-off value of 5.6 mmol/L, the Dagang DRS (AUC: 0.616; 95% CI, 0.592–0.641) was better than the FPG value alone (AUC: 0.571; 95% CI, 0.546–0.596) in participants with FPG <6.1 mmol/L (n=1545, P=0.028). CONCLUSIONS: Dagang DRS is a valuable tool for detecting dysglycemia, especially when FPG <6.1 mmol/L, in oil field workers in China. International Scientific Literature, Inc. 2017-06-11 /pmc/articles/PMC5475373/ /pubmed/28601890 http://dx.doi.org/10.12659/MSM.904449 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Tian, Xiubiao
Liu, Yan
Han, Ying
Shi, Jieli
Zhu, Tiehong
Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title_full Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title_fullStr Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title_full_unstemmed Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title_short Risk Score for Detecting Dysglycemia: A Cross-Sectional Study of a Working-Age Population in an Oil Field in China
title_sort risk score for detecting dysglycemia: a cross-sectional study of a working-age population in an oil field in china
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475373/
https://www.ncbi.nlm.nih.gov/pubmed/28601890
http://dx.doi.org/10.12659/MSM.904449
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