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BET proteins are a key component of immunoglobulin gene expression

AIM: BET proteins have been shown to regulate gene expression including inflammatory genes. METHODS: In order to investigate the role of the BET proteins in immunoglobulin production we treated the human B-cell line CLNH11.4 and primary human B cells and ozone-exposed mice with BET inhibitors (JQ1 o...

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Detalles Bibliográficos
Autores principales:	Shim, Jung Min, Lee, Jin S, Russell, Kirsty E, Wiegman, Coen H, Barnes, Peter J, Fear, David, Adcock, Ian M, Durham, Andrew L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476213/ https://www.ncbi.nlm.nih.gov/pubmed/28322577 http://dx.doi.org/10.2217/epi-2016-0147

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