Hepatic microvascular dysfunction and increased advanced glycation end products are components of non-alcoholic fatty liver disease

BACKGROUND: This study aimed to investigate the pathophysiology of hepatic microcirculatory dysfunction in non-alcoholic fatty liver disease (NAFLD). METHODS: In Wistar rats, NAFLD model was induced by 20 weeks of high-fat diet (HFD) feeding. Rolling and adhesion of leukocytes and tissue perfusion i...

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Detalles Bibliográficos
Autores principales: Pereira, Evelyn Nunes Goulart da Silva, Silvares, Raquel Rangel, Flores, Edgar Eduardo Ilaquita, Rodrigues, Karine Lino, Ramos, Isalira Peroba, da Silva, Igor José, Machado, Marcelo Pelajo, Miranda, Rosiane Aparecida, Pazos-Moura, Carmen Cabanelas, Gonçalves-de-Albuquerque, Cassiano F., Faria-Neto, Hugo Caire de Castro, Tibiriça, Eduardo, Daliry, Anissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476253/
https://www.ncbi.nlm.nih.gov/pubmed/28628674
http://dx.doi.org/10.1371/journal.pone.0179654

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