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ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction
Estrogen-related receptor α (ERRα) is a member of the nuclear receptor superfamily controlling energy homeostasis; however, its precise role in regulating antiviral innate immunity remains to be clarified. Here, we showed that ERRα deficiency conferred resistance to viral infection both in vivo and...
Autores principales: | He, Xiang, Ma, Shengli, Tian, Yinyin, Wei, Congwen, Zhu, Yongjie, Li, Feng, Zhang, Pingping, Wang, Penghao, Zhang, Yanhong, Zhong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476288/ https://www.ncbi.nlm.nih.gov/pubmed/28591144 http://dx.doi.org/10.1371/journal.ppat.1006347 |
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