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MicroRNA-433-3p promotes osteoblast differentiation through targeting DKK1 expression

Dickkopf-1 (DKK1) is a powerful antagonist of canonical WNT signaling pathway, and is regarded as a biomarker for osteoporosis. Its expression is highly correlated with bone mass and osteoblasts maturation. In this study, mouse primary bone marrow cells and osteoblast cell lines were used. Luciferas...

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Detalles Bibliográficos
Autores principales: Tang, Xiaolin, Lin, Jiantao, Wang, Guanhai, Lu, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476290/
https://www.ncbi.nlm.nih.gov/pubmed/28628652
http://dx.doi.org/10.1371/journal.pone.0179860