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APPswe/PS1dE9 mice with cortical amyloid pathology show a reduced NAA/Cr ratio without apparent brain atrophy: A MRS and MRI study

Transgenic animal models of Aβ pathology provide mechanistic insight into some aspects of Alzheimer disease (AD) pathology related to Aβ accumulation. Quantitative neuroimaging is a possible aid to improve translation of mechanistic findings in transgenic models to human end phenotypes of brain morp...

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Detalles Bibliográficos
Autores principales:	Kuhla, Angela, Rühlmann, Claire, Lindner, Tobias, Polei, Stefan, Hadlich, Stefan, Krause, Bernd J., Vollmar, Brigitte, Teipel, Stefan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476467/ https://www.ncbi.nlm.nih.gov/pubmed/28652970 http://dx.doi.org/10.1016/j.nicl.2017.06.009

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