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Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling

The molecular mechanisms of thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear. Therefore, we hypothesize that TB4 influences HSC activation through hedgehog (Hh) pathway. HSC functions declined in a TB4 siRNA-treated LX-2. TB4 suppression down-regulate...

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Detalles Bibliográficos
Autores principales:	Kim, Jieun, Hyun, Jeongeun, Wang, Sihyung, Lee, Chanbin, Lee, Jae-Wook, Moon, Eun-Yi, Cha, Heejae, Diehl, Anna Mae, Jung, Youngmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476572/ https://www.ncbi.nlm.nih.gov/pubmed/28630423 http://dx.doi.org/10.1038/s41598-017-03782-x

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