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Computational method allowing Hydrogen-Deuterium Exchange Mass Spectrometry at single amide Resolution

Hydrogen-deuterium exchange (HDX) coupled with mass spectrometry (HDXMS) is a rapid and effective method for localizing and determining protein stability and dynamics. Localization is routinely limited to a peptide resolution of 5 to 20 amino acid residues. HDXMS data can contain information beyond...

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Detalles Bibliográficos
Autores principales:	Gessner, Chris, Steinchen, Wieland, Bédard, Sabrina, J. Skinner, John, Woods, Virgil L., Walsh, Thomas J., Bange, Gert, Pantazatos, Dionysios P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476592/ https://www.ncbi.nlm.nih.gov/pubmed/28630467 http://dx.doi.org/10.1038/s41598-017-03922-3

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