Interatrial shunt devices for heart failure with normal ejection fraction: a technology update

Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due...

Descripción completa

Detalles Bibliográficos
Autores principales: Cuthbert, Joseph J, Pellicori, Pierpaolo, Clark, Andrew L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476655/
https://www.ncbi.nlm.nih.gov/pubmed/28652826
http://dx.doi.org/10.2147/MDER.S113105
_version_ 1783244632362057728
author Cuthbert, Joseph J
Pellicori, Pierpaolo
Clark, Andrew L
author_facet Cuthbert, Joseph J
Pellicori, Pierpaolo
Clark, Andrew L
author_sort Cuthbert, Joseph J
collection PubMed
description Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review.
format Online
Article
Text
id pubmed-5476655
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-54766552017-06-26 Interatrial shunt devices for heart failure with normal ejection fraction: a technology update Cuthbert, Joseph J Pellicori, Pierpaolo Clark, Andrew L Med Devices (Auckl) Review Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review. Dove Medical Press 2017-06-02 /pmc/articles/PMC5476655/ /pubmed/28652826 http://dx.doi.org/10.2147/MDER.S113105 Text en © 2017 Cuthbert et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Cuthbert, Joseph J
Pellicori, Pierpaolo
Clark, Andrew L
Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title_full Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title_fullStr Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title_full_unstemmed Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title_short Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
title_sort interatrial shunt devices for heart failure with normal ejection fraction: a technology update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476655/
https://www.ncbi.nlm.nih.gov/pubmed/28652826
http://dx.doi.org/10.2147/MDER.S113105
work_keys_str_mv AT cuthbertjosephj interatrialshuntdevicesforheartfailurewithnormalejectionfractionatechnologyupdate
AT pellicoripierpaolo interatrialshuntdevicesforheartfailurewithnormalejectionfractionatechnologyupdate
AT clarkandrewl interatrialshuntdevicesforheartfailurewithnormalejectionfractionatechnologyupdate

Ejemplares similares