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Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers

In order to identify reliable markers of corneal epithelial stem cells, we employed an inducible transgenic “pulse-chase” murine model (K5Tta × TRE-H2BGFP) to localize, purify, and characterize slow cycling cells in the cornea. The retention of GFP labeling in slowly dividing cells allowed for local...

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Detalles Bibliográficos
Autores principales: Sartaj, R., Zhang, C., Wan, P., Pasha, Z., Guaiquil, V., Liu, A., Liu, J., Luo, Y., Fuchs, E., Rosenblatt, M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476663/
https://www.ncbi.nlm.nih.gov/pubmed/28630424
http://dx.doi.org/10.1038/s41598-017-04006-y