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Chronic treatment with a smart antioxidative nanoparticle for inhibition of amyloid plaque propagation in Tg2576 mouse model of Alzheimer’s disease

The present study aimed to assess whether our newly developed redox nanoparticle (RNP(N)) that has antioxidant potential decreases Aβ levels or prevents Aβ aggregation associated with oxidative stress. The transgenic Tg2576 Alzheimer’s disease (AD) mice were used to investigate the effect of chronic...

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Detalles Bibliográficos
Autores principales: Boonruamkaew, Phetcharat, Chonpathompikunlert, Pennapa, Vong, Long Binh, Sakaue, Sho, Tomidokoro, Yasushi, Ishii, Kazuhiro, Tamaoka, Akira, Nagasaki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476667/
https://www.ncbi.nlm.nih.gov/pubmed/28630497
http://dx.doi.org/10.1038/s41598-017-03411-7

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