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Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection
A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments, we sugg...
Autores principales: | Wodarz, Dominik, Levy, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476677/ https://www.ncbi.nlm.nih.gov/pubmed/28630490 http://dx.doi.org/10.1038/s41598-017-04130-9 |
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