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Long-Read Isoform Sequencing Reveals a Hidden Complexity of the Transcriptional Landscape of Herpes Simplex Virus Type 1

In this study, we used the amplified isoform sequencing technique from Pacific Biosciences to characterize the poly(A)(+) fraction of the lytic transcriptome of the herpes simplex virus type 1 (HSV-1). Our analysis detected 34 formerly unidentified protein-coding genes, 10 non-coding RNAs, as well a...

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Detalles Bibliográficos
Autores principales:	Tombácz, Dóra, Csabai, Zsolt, Szűcs, Attila, Balázs, Zsolt, Moldován, Norbert, Sharon, Donald, Snyder, Michael, Boldogkői, Zsolt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476775/ https://www.ncbi.nlm.nih.gov/pubmed/28676792 http://dx.doi.org/10.3389/fmicb.2017.01079

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