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NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

NAD(+) is a vital redox cofactor and a substrate required for activity of various enzyme families, including sirtuins and poly(ADP-ribose) polymerases. Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease,...

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Detalles Bibliográficos
Autores principales:	Ratajczak, Joanna, Joffraud, Magali, Trammell, Samuel A. J., Ras, Rosa, Canela, Núria, Boutant, Marie, Kulkarni, Sameer S., Rodrigues, Marcelo, Redpath, Philip, Migaud, Marie E., Auwerx, Johan, Yanes, Oscar, Brenner, Charles, Cantó, Carles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476803/ https://www.ncbi.nlm.nih.gov/pubmed/27725675 http://dx.doi.org/10.1038/ncomms13103

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