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Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

The zebrafish possesses a remarkable capacity of adult heart regeneration, but the underlying mechanisms are not well understood. Here we report that chromatin remodelling factor Brg1 is essential for adult heart regeneration. Brg1 mRNA and protein are induced during heart regeneration. Transgenic o...

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Detalles Bibliográficos
Autores principales: Xiao, Chenglu, Gao, Lu, Hou, Yu, Xu, Congfei, Chang, Nannan, Wang, Fang, Hu, Keping, He, Aibin, Luo, Ying, Wang, Jun, Peng, Jinrong, Tang, Fuchou, Zhu, Xiaojun, Xiong, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476829/
https://www.ncbi.nlm.nih.gov/pubmed/27929112
http://dx.doi.org/10.1038/ncomms13787