Cargando…
Dab1 Contributes to Angiotensin II-Induced Apoptosis via p38 Signaling Pathway in Podocytes
Numerous studies have found that angiotensin II (Ang II) participates in podocyte apoptosis and exacerbates progression of end-stage kidney disease (ESKD). However, its underlying mechanism remains largely unexplored. As a homolog of Drosophila disabled (Dab) protein, Dab1 plays a vital role in cyto...
Autores principales: | Gao, Zhao, Chen, Xinghua, Zhu, Kai, Zeng, Ping, Ding, Guohua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476836/ https://www.ncbi.nlm.nih.gov/pubmed/28676854 http://dx.doi.org/10.1155/2017/2484303 |
Ejemplares similares
-
Angiotensin II induces cholesterol accumulation and injury in podocytes
por: Yang, Yingjie, et al.
Publicado: (2017) -
Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: roleof c-Abl
por: Yang, Qian, et al.
Publicado: (2016) -
The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes
por: Wennmann, D O, et al.
Publicado: (2014) -
Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis
por: Hsu, Hsiang-Hao, et al.
Publicado: (2011) -
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway
por: Zhu, Zijing, et al.
Publicado: (2021)