Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH

We have recently shown that hepatocyte-specific c-met deficiency accelerates the progression of nonalcoholic steatohepatitis in experimental murine models resulting in augmented production of reactive oxygen species and accelerated development of fibrosis. The aim of this study focuses on the elucid...

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Detalles Bibliográficos
Autores principales: Ramadori, Pierluigi, Drescher, Hannah, Erschfeld, Stephanie, Fragoulis, Athanassios, Kensler, Thomas W., Wruck, Christoph Jan, Cubero, Francisco Javier, Trautwein, Christian, Streetz, Konrad L., Kroy, Daniela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476895/
https://www.ncbi.nlm.nih.gov/pubmed/28676836
http://dx.doi.org/10.1155/2017/3420286

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