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Nutrients required for phospholipid synthesis are lower in blood and cerebrospinal fluid in mild cognitive impairment and Alzheimer's disease dementia

INTRODUCTION: Synaptic membrane formation depends on nutrients that fuel metabolic pathways for the synthesis of constituent phospholipids. Consequently, insufficient availability of such nutrients may restrict membrane formation and contribute to synaptic dysfunction in Alzheimer's disease (AD...

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Detalles Bibliográficos
Autores principales:	van Wijk, Nick, Slot, Rosalinde E.R., Duits, Flora H., Strik, Marieke, Biesheuvel, Egbert, Sijben, John W.C., Blankenstein, Marinus A., Bierau, Jörgen, van der Flier, Wiesje M., Scheltens, Philip, Teunissen, Charlotte E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Blood Based Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476966/ https://www.ncbi.nlm.nih.gov/pubmed/28653034 http://dx.doi.org/10.1016/j.dadm.2017.04.005

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