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Palladium-catalyzed ligand-promoted site-selective cyanomethylation of unactivated C(sp(3))–H bonds with acetonitrile

The direct cyanomethylation of unactivated sp(3) C–H bonds of aliphatic amides was achieved via palladium catalysis assisted by a bidentate directing group with good functional group compatibility. This process represents the first example of the direct cross-coupling of sp(3) C–H bonds with acetoni...

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Detalles Bibliográficos
Autores principales:	Liu, Yongbing, Yang, Ke, Ge, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477045/ https://www.ncbi.nlm.nih.gov/pubmed/28660057 http://dx.doi.org/10.1039/c5sc04066c

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