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Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

BACKGROUND: The protein kinase C (PKC) family comprises central regulators of multiple signal transduction processes and is involved in the progression of many cancers. Nuclear factor Kappa-B (NF-κB) is constitutively expressed in cancer tissues and stimulates the transcription of various tumor-rela...

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Detalles Bibliográficos
Autores principales: Zheng, Jin, Kong, Chuize, Yang, Xiaoxi, Cui, Xiaolu, Lin, Xuyong, Zhang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477139/
https://www.ncbi.nlm.nih.gov/pubmed/28629334
http://dx.doi.org/10.1186/s12885-017-3401-7