Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement

BACKGROUND: Natural IgM antibodies (Abs) function as innate immune sensors of injury via recognition of neoepitopes expressed on damaged cells, although how this recognition systems function following spinal cord injury (SCI) exposes various neoepitopes and their precise nature remains largely unkno...

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Detalles Bibliográficos
Autores principales: Narang, Aarti, Qiao, Fei, Atkinson, Carl, Zhu, Hong, Yang, Xiaofeng, Kulik, Liudmila, Holers, V. Michael, Tomlinson, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477255/
https://www.ncbi.nlm.nih.gov/pubmed/28629465
http://dx.doi.org/10.1186/s12974-017-0894-6

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