Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601

Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insi...

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Detalles Bibliográficos
Autores principales: Zong, Gongli, Zhong, Chuanqing, Fu, Jiafang, Qin, Ronghuo, Cao, Guangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477335/
https://www.ncbi.nlm.nih.gov/pubmed/28522727
http://dx.doi.org/10.1128/genomeA.00385-17
Descripción
Sumario:Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insights into the genetic basis of tacrolimus biosynthesis and regulation.

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